a drug that interacts with adrenoceptors in the brain to reduce sympathetic stimulation of the arteries (see catecholamine, noradrenaline). It is occasionally used to treat high blood pressure; administered by mouth or injection, it commonly causes drowsiness and dry mouth, and sudden withdrawal may worsen the hypertension.
Trade names:
In the clonidine suppression test, used in the diagnosis of phaeochromocytoma, clonidine is administered orally and plasma catecholamines sampled then and at hourly intervals for 3 hours. In normal subjects clonidine suppresses release of catecholamines and plasma levels are reduced, but in people with phaeochromocytoma plasma catecholamines remain elevated.

The new mediacal dictionary. 2014.

Look at other dictionaries:

  • Clonidine — Général Nom IUPAC N (2,6 dichlorophényl) 4,5 dihydro 1H imidazol 2 amine N …   Wikipédia en Français

  • clonidine — [klän′ə dēn΄, klän′ədin; klō′nədēn, klō′nədin] n. a white, crystalline drug, C9H9Cl2N3·HCl, taken orally, used to lower high blood pressure and, experimentally, to ease withdrawal from narcotics: in full clonidine hydrochloride …   English World dictionary

  • clonidine — ● clonidine nom féminin Médicament hypotenseur agissant sur le centre bulbaire de contrôle de la tension artérielle …   Encyclopédie Universelle

  • Clonidine — Not to be confused with clomifene or Klonopin. Clonidine Systematic (IUPAC) name N (2,6 dichlorophenyl) 4,5 dihydro 1H imidazol 2 amine …   Wikipedia

  • clonidine — noun Etymology: chlor + aniline + imide + 2 ine Date: 1970 an antihypertensive drug C9H9Cl2N3 used especially to treat essential hypertension, to prevent migraine headache, and to …   New Collegiate Dictionary

  • clonidine — Centrally acting anti hypertensive agent that works by inhibiting activity of the sympathoexcitatory neurons that regulate arterial pressure. Considered to be a mixed agonist acting on both alpha 2 adrenoreceptors and imidazoline receptors (I1 R) …   Dictionary of molecular biology

  • clonidine — /klon i deen , kloh ni /, n. Pharm. a synthetic white crystalline substance, C9H9Cl2N3, used in the treatment of high blood pressure. [1965 70; C(H)LO(RO) 2 + (A)NI(LINE) + (IMI)D(E), extracted from the chemical name + INE2] * * * …   Universalium

  • clonidine — noun A drug traditionally prescribed for hypertension, having the chemical formula CHClN, and acting by stimulating α2 receptors in the brain …   Wiktionary

  • clonidine — clo·ni·dine klän ə .dēn, klōn , .dīn n an antihypertensive drug used in the form of its hydrochloride C9H9Cl2N3·HCl esp. to treat essential hypertension, to prevent migraine headache, and to diminish opiate withdrawal symptoms * * * n. a drug… …   Medical dictionary

  • clonidine — clo·ni·dine …   English syllables

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